First-generation epigenetic clocks
3 papers1 finding
- Human trial1
- Humans2
Interventions
1Dasatinib + quercetin
upin humans1
1 study
Dasatinib + quercetin
upin humans1
Dasatinib + quercetin increases first-generation epigenetic clocks in humans.
“Significant increases in epigenetic age acceleration were observed in first-generation epigenetic clocks and mitotic clocks at 3 and 6 months”
Human trial6 monthsn = 19
Aging22 Feb 2024
Latest
7 in 12 monthsResearch Square
Low back pain, disability, and biological aging: routinely measurable clinical clocks versus epigenetic clocks (NHANES)
Preprint: cross-sectional study of 2,532 peopleLow back pain
Current HIV/AIDS Reports
Epigenetic aging is a hallmark of HIV pathogenesis and phenotypic outcomes
ReviewBiomarkers
GSA 2025 Abstract
Sense of Control and Epigenetic Aging: The Mediating Role of Lifestyle Behaviors
Cohort study of 1,255 peoplePopulations
GSA 2025 Abstract
An estimate of the pace of aging from a single brain scan predicts chronic disease, dementia, and mortality
Cohort study of 42,583 peopleBiomarkers
Nature Communications
An unbiased comparison of 14 epigenetic clocks in relation to 174 incident disease outcomes
Cohort study of 18,859 peopleEpigenetic clock
medRxiv
Epigenetic clocks of biological aging and risk of incident mild cognitive impairment and dementia: the Women's Health Initiative Memory Study
Preprint: cohort study of 6,069 peopleMild cognitive impairment
Aging
Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions
Non-randomised trial in 19 peopleSenolytics
Clinical Epigenetics
Epigenetic age acceleration mediates the association between smoking and diabetes-related outcomes
Cohort study of 2,474 peopleDiabetes