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Friday, November 13

International Journal of Molecular Sciences

Fatty acid altered DNA marks in human fat-derived stem cells

A measure of chemical tagging on nuclear DNA fell from 29.87% in untreated cells to 26.84% after exposure to a saturated fatty acid.A measure of chemical tagging on nuclear DNA fell from 29.87% in untreated cells to 26.84% after exposure to a saturated fatty acid.

Figure from International Journal of Molecular Sciences
Experiments in cellsMechanisms
Research Square

Blood DNA screen false positives rose with age

False-positive rates rose from 0.3% below age 60 to 7.5% at 80 or older in an analysis of whole-blood samples.False-positive rates rose from 0.3% below age 60 to 7.5% at 80 or older in an analysis of whole-blood samples.

Blood cells with densely marked nuclei sit beside white-haired figures, surrounded by smaller clusters with sparse marks and dark-haired figures.
Preprint: cross-sectional studyBiomarkers

Thursday, November 12

Wednesday, November 11

Nature

Immune signal keeps brown fat in a low-heat state in mice

Blocking a hormone receptor for one week restored heat production in mice aged 70–75 weeks, as experiments traced immune control of brown fat.Blocking a hormone receptor for one week restored heat production in mice aged 70–75 weeks, as experiments traced immune control of brown fat.

H6PD protein expression is enriched in BA-L cells.
Mouse studyImmune response