PRSEUR_replace+TPMI

1. PRSEUR_replace+TPMI raises the risk of breast cancer in humans (2.09-fold increased risk).

   Humanstop 5% vs 40th to 60th percentile

   Population-specific optimization of polygenic risk scores for breast cancer in East Asians · Genetics in medicine open · 3 Aug 2026

2. PRSEUR_replace+TPMI predicts breast cancer in humans (OR 1.51, 95% CI 1.39-1.63).

   Humansin East Asiansn = 46,422

   Population-specific optimization of polygenic risk scores for breast cancer in East Asians · Genetics in medicine open · 3 Aug 2026

Breast cancer →