Proton conductance

1. UCP3 decreases proton conductance in mice.

   “Absence of uncoupling protein-3 leads to greater activation of an adenine nucleotide translocase-mediated proton conductance in skeletal muscle mitochondria from calorie restricted mice”

   Animalsunder calorie restrictionskeletal muscle

   Absence of uncoupling protein-3 leads to greater activation of an adenine nucleotide translocase-mediated proton conductance in skeletal muscle mitochondria from calorie restricted mice

   Biochimica et biophysica acta·3 Mar 2010

More on UCP3

1. Metabolic intensity is associated with proton conductance in mice.

   “Mitochondria isolated from the skeletal muscle of mice in the upper quartile had higher proton conductance”

   Animalsskeletal muscle

   Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer

   Aging cell·1 Jun 2004