Maximal leak-dependent respiration

1. Caloric restriction decreases maximal leak-dependent respiration in mice.

   “short-term CR (2 weeks) in wild-type (Wt) mice resulted in a lowering of the maximal leak-dependent respiration in skeletal muscle mitochondria”

   Animalsin wild-type miceskeletal muscle2 weeks

   Absence of uncoupling protein-3 leads to greater activation of an adenine nucleotide translocase-mediated proton conductance in skeletal muscle mitochondria from calorie restricted mice

   Biochimica et biophysica acta·3 Mar 2010

More on Caloric restriction