ProtAgeGap

1. Exercise decreases ProtAgeGap in humans (equivalent of 10 months).

   “In a 12-week supervised exercise study (MyoGlu) in 26 men, ProtAgeGap decreased by the equivalent of 10 months.”

   Human trial12 weeksmalesn = 26

   Reversal of proteomic aging with exercise-results from the UK biobank and a 12-week intervention study

   npj aging·26 Dec 2025

More on Exercise

1. ProtAgeGap is associated with physical activity in humans.

   “higher proteomic aging score (ProtAgeGap) was linked to lower physical activity”

   Humansn = 45,438

   Reversal of proteomic aging with exercise-results from the UK biobank and a 12-week intervention study

   npj aging·26 Dec 2025

More on Physical activity

1. ProtAgeGap raises the risk of type 2 diabetes in humans.

   “higher proteomic aging score (ProtAgeGap) was linked to lower physical activity and increased risk of type 2 diabetes”

   Humansn = 45,438

   Reversal of proteomic aging with exercise-results from the UK biobank and a 12-week intervention study

   npj aging·26 Dec 2025

More on Type 2 diabetes