Pro-fibrotic markers

There are 2 papers on pro-fibrotic markers in aging research: none in people yet, 2 in cells.

2 papers study it5 more mention it1 finding

See all 7 papers on pro-fibrotic markers

Cells2

Interventions

1

Doxorubicin

upin cells1

1 study

Doxorubicin increases pro-fibrotic markers in cells (doxorubicin-induced senescence in alveolospheres).
“senescence-inducing conditions were associated with an increase in senescence-associated, pro-fibrotic, inflammatory, and matrix-modulating markers”
Cellsdoxorubicin-induced senescence in alveolospheres24 h
Senescent Alveolospheres: A Preliminary 3D Model for Exploring Epithelial Senescence and Pro-Fibrotic Signaling
International journal of molecular sciencesJul 10, 2026

More on Doxorubicin

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1 paper in 12 months

International Journal of Molecular SciencesJul 28

Senescent Alveolospheres: A Preliminary 3D Model for Exploring Epithelial Senescence and Pro-Fibrotic Signaling

Experiments in cellsCellular senescence

Acta BiomaterialiaApr 30

Age-dependent functional crosstalk between cardiac fibroblasts and cardiomyocytes in a 3D engineered cardiac tissue

Experiments in cellsMechanisms

BMC OphthalmologyJul 2

Corneal oxidative stress, inflammation, and senescence as key drivers of ocular pathology in a chronic graft-versus-host disease model

Experiments in miceCellular senescence

SLAS DiscoveryMar 3

A secretome screen in primary human lung fibroblasts identifies FGF9 as a novel regulator of cellular senescence

Experiments in human cellsCellular senescence

Biomedicine & PharmacotherapySep 30

Disruption of IL-18 signaling via engineered IL-18BP biologics alleviates experimental cholestatic liver disease

Experiments in rodentsInterventions

Respiratory InvestigationSep 24

A novel BRD4 degrader, ARV-825, attenuates lung fibrosis through senolysis and antifibrotic effect

Experiments in miceIdiopathic pulmonary fibrosis

AgingDec 20

Platelet-derived β2m regulates age related monocyte/macrophage functions

Experiments in miceMechanisms