Cardiac fibroblasts

Cardiac fibroblasts has been studied in 1 paper since 2017: none in people yet, 1 in cells. No study of it in people or animals has been published yet. The newest paper, Apr 25, 2017: “Age-dependent functional crosstalk between cardiac fibroblasts and cardiomyocytes in a 3D engineered cardiac tissue”.

Intervention

1 paper studies it1 findingUpdated

See all 1 papers on cardiac fibroblasts

At a glance

The findings reach cells, none yet in people. 1 lab in 1 country.

Cells: a single group. Worms or flies, mice and humans: nothing yet.
  • 1 lab in 1 country
  • Funders: American Heart Association and 3 more
  • Cells1

What did studies of cardiac fibroblasts find?

1

Studies of cardiac fibroblasts measured one outcome, cardiomyocyte electrical and mechanical function.

Cardiomyocyte electrical and mechanical function

downin cells1

1 study
  1. Cardiac fibroblasts impair cardiomyocyte electrical and mechanical function in cells (3D co-culture with cardiomyocytes; comparison with fetal cardiac fibroblasts).

    “in vitro expanded adult, but not fetal, cardiac fibroblasts significantly deteriorated electrical and mechanical function of the co-cultured cardiomyocytes”

    Cells3D co-culture with cardiomyocytes; comparison with fetal cardiac fibroblastsin vitro expandedengineered cardiac tissue

    Age-dependent functional crosstalk between cardiac fibroblasts and cardiomyocytes in a 3D engineered cardiac tissue

    Acta biomaterialia

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