Polygenic score for bioavailable testosterone

1. Polygenic score for bioavailable testosterone has no effect on change in bioavailable testosterone in humans.

   “A PGS for BAT, strongly associated with baseline levels (P = 2.2 × 10-16, R2=0.16), was not associated with BAT decline over time.”

   HumansserumMean follow-up: 4.3 yearsmalesn = 6,354

   Role of genetics in the age-related testosterone decline in men: a UK Biobank study

   European journal of endocrinology·17 Jul 2025

More on Change in bioavailable testosterone

1. Polygenic score for bioavailable testosterone is associated with baseline bioavailable testosterone in humans (R2=0.16).

   “A PGS for BAT, strongly associated with baseline levels (P = 2.2 × 10-16, R2=0.16), was not associated with BAT decline over time.”

   Humansserummalesn = 6,354

   Role of genetics in the age-related testosterone decline in men: a UK Biobank study

   European journal of endocrinology·17 Jul 2025

More on Baseline bioavailable testosterone