Change in bioavailable testosterone

1. Polygenic score for bioavailable testosterone has no effect on change in bioavailable testosterone in humans.

   “A PGS for BAT, strongly associated with baseline levels (P = 2.2 × 10-16, R2=0.16), was not associated with BAT decline over time.”

   HumansserumMean follow-up: 4.3 yearsmalesn = 6,354

   Role of genetics in the age-related testosterone decline in men: a UK Biobank study

   European journal of endocrinology·17 Jul 2025

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