Baseline bioavailable testosterone
2 findings
Associations
2Polygenic score for bioavailable testosterone
mixedin humans1
1 study
Polygenic score for bioavailable testosterone
mixedin humans1
Polygenic score for bioavailable testosterone is associated with baseline bioavailable testosterone in humans (R2=0.16).
“A PGS for BAT, strongly associated with baseline levels (P = 2.2 × 10-16, R2=0.16), was not associated with BAT decline over time.”
Humansserummalesn = 6,354
Role of genetics in the age-related testosterone decline in men: a UK Biobank study
European journal of endocrinology17 Jul 2025
Relative change in bioavailable testosterone
downin humans1
1 study
Relative change in bioavailable testosterone
downin humans1
Baseline bioavailable testosterone is associated with relative change in bioavailable testosterone in humans.
“baseline levels of BAT, T, and SHBG were each negatively associated with their respective relative changes at follow-up (all P < .001).”
HumansserumMean follow-up: 4.3 yearsmalesn = 6,354
Role of genetics in the age-related testosterone decline in men: a UK Biobank study
European journal of endocrinology17 Jul 2025