PI3K/AKT phosphorylation
Biomarker1 paper1 finding
- Animals1
Upstream
1PIRB
is required forin mouse cells1
1 study
PIRB
is required forin mouse cells1
PIRB is required for PI3K/AKT phosphorylation in mouse cells.
Cellsrequired for inhibition by recombinant ANGPTL8; shown by PirB knockdown
A metabolic protein promotes blood stem cell aging in mice · Biogerontology · 8 Oct 2026
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2BiogerontologyAnimals
A metabolic protein promotes blood stem cell aging in mice
In mice, genetically removing the protein reduced signs of cellular aging across multiple tissues and limited hallmarks of blood stem cell aging.In mice, genetically removing the protein reduced signs of cellular aging across multiple tissues and limited hallmarks of blood stem cell aging.