Papers on physical dysfunction

143 papers2 new in 30 days

Wednesday, October 28

Spine Surgery and Related ResearchOct 28

Psychological Burden in Adult Spinal Deformity Is Associated with Disability, Frailty, and Physical Function Rather Than Radiographic Severity

Cross-sectional study of 142 peopleBiomarkers

Paper

Saturday, October 10

Physiological ReportsOct 10

Adding Tat-Beclin1 to an endurance training program promotes additive improvements in physical function in aged male mice

Experimental design. Mice underwent physical function testing before the intervention, including a familiarization period followed by baseline testing.

Experiments in miceEndurance training

Paper

Tuesday, July 7

Journal of the American Medical Directors AssociationJul 7

Cerebral Microvascular Injury and Physical Function in Older Patients With Atrial Fibrillation: Evidence for Sex-Specific Patterns

Cross-sectional study in peopleAtrial fibrillation

Paper

Thursday, July 2

Supportive Care in CancerJul 2

Feasibility and preliminary effects of combined exercise and nutritional intervention on muscle mass preservation during chemoradiotherapy for head and neck cancer: a prospective study

Non-randomized trial in 29 peopleExercise

Paper

Wednesday, July 1

JCSM CommunicationsJul 1

A Possible Association of Elevated Delta‐Like Protein 4 Concentration With Low Walking Speed and Low Handgrip Strength in Japanese Older Adults

Cross-sectional study of 283 peopleWalking speed

Paper

Tuesday, May 26

MetabolitesMay 26

Atherogenic Index of Plasma Relationship with Cardiovascular Risk Factors and Frailty and Value as Determinant of Mortality in Elderly Patients with Severe Aortic Stenosis

Cohort study of 102 peopleAtherogenic index of plasma

Paper

Monday, April 27

Health Care ScienceApr 27

Health Influence and Association Analysis of Inpatient Service Under-Utilization in Older Adults With Multimorbidities: A National Study in China

Cohort study of 3,636 peopleMultimorbidity

Paper

Sunday, April 12

BoneApr 12

Association of intradialytic hypotension and physical performance with fall and fracture incidence in hemodialysis patients: The REPnet-HD study

Cohort study of 518 peopleBone fracture

Paper

Friday, March 27

Circulation ReportsMar 27

Prevalence and Prognostic Impact of Physical Dysfunction, Cachexia, and Dysphagia in Older Patients With Heart Failure

Cohort study of 468 peopleCachexia

Paper

Saturday, March 21

Journal of Renal NutritionMar 21

Association Between Sarcopenic Obesity and Worsening Physical Performance in Patients Undergoing Hemodialysis: The REPnet-HD Study

Cohort study of 295 peopleSarcopenic obesity

Paper

Friday, March 6

Aging CellMar 6

Decreased Glucose Metabolism and Declined Chaperones Are Unique Features Required for the Survival of Senescent Fibroblasts and Pyruvate Dehydrogenase Is a Potent Senolytic Target

Experiments in miceInterventions

Paper

Wednesday, February 25

ChemRxivFeb 25

Pyrroloquinoline quinone and imidazopyrroloquinoline intake extend healthy lifespan and improve physical dysfunctions with age in mice

Preprint: experiments in miceInterventions

Paper

Tuesday, February 24

The Journal of PhysiologyFeb 24

Translational studies of chronic supplementation with a mitochondria-targeted antioxidant to improve physical function with ageing

Randomized trial in 26 peopleInterventions

Paper

Saturday, February 21

BMC Public HealthFeb 21

Joint association of physical function and sleep duration with incident depressive symptoms among middle-aged and older Chinese

Cohort study of 6,189 peopleDepressive symptoms

Paper

Wednesday, February 18

ChemRxivFeb 18

Pyrroloquinoline quinone and imidazopyrroloquinoline intake extend healthy lifespan and improve physical dysfunctions with age in mice

Preprint: experiments in miceInterventions

Paper

Wednesday, January 28

DiagnosticsJan 28

Immediate Effect of Whole-Body Vibration Exercise Performed in Vertical Versus Side-Alternating Displacement Modes on Physiological Parameters, Perception of Effort, Strength and Functionality in Adults with Obesity

Randomized trial in 72 peopleObesity

Paper

Saturday, January 3

GSA 2025 AbstractJan 3

Machine-Learning-Based Prediction and Risk for Possible Sarcopenia Among Community-Dwelling Older Adults

Cohort study of 1,761 peoplePossible sarcopenia

Paper

Tuesday, December 30

Aging CellDec 30

Senolytic-Resistant Senescent Cells Have a Distinct SASP Profile and Functional Impact: The Path to Developing Senosensitizers

Experiments in miceSenescence-associated secretory phenotype (SASP)

Paper

Wednesday, December 17

European Geriatric MedicineDec 17

Skeletal muscle thickness and echo intensity may reflect the risk of malnutrition and physical dysfunction in acutely hospitalized older patients

Cross-sectional study of 59 peopleMalnutrition

Paper

Monday, November 17

Journal of Cachexia, Sarcopenia and MuscleNov 17

Rise and Fall of Physical Capacity in a General Population: A 47-Year Longitudinal Study

Cohort study of 427 peoplePopulations

Paper

Saturday, November 8

Current Heart Failure ReportsNov 8

Multiprofessional Interventions for Frailty in Patients with Heart Failure: A Comprehensive Review

ReviewHeart failure

Paper

Monday, November 3

AHA Scientific Sessions 2025 AbstractNov 3

Symptoms of Bladder Incontinence Are Associated with Worse Functional Status and Quality of Life in Heart Failure with Preserved Ejection Fraction

Cohort study of 193 peopleUrinary incontinence

Paper

Wednesday, October 29

PLOS OneOct 29

Social isolation and cardiometabolic burden synergistically predict physical dysfunction in aging Chinese adults: Evidence of risk thresholds and the mediating role of frailty

Cross-sectional study of 3,756 peoplePopulations

Paper

Saturday, October 11

Aging Clinical and Experimental ResearchOct 11

Abnormal maximal tubular reabsorption of phosphate as a novel biomarker of physical dysfunction in older adults

Cohort study in peopleBiomarkers

Paper

Monday, September 22

Journal of Functional Morphology and KinesiologySep 22

Muscle Fiber Recruitment Characteristics in Trained Older Adults: An EMG Frequency Analysis During Voluntary Contraction

Cross-sectional study of 50 peopleMuscle

Paper

Friday, September 5

bioRxivSep 5

Senolytic-Resistant Senescent Cells Have a Distinct SASP Profile and Functional Impact: The Path to Developing Senosensitizers

Preprint: experiments in miceSenolytics

Paper

Tuesday, September 2

AgingSep 2

Glycocalyx-targeted therapy prevents age-related muscle loss and declines in maximal exercise capacity

Experiments in miceMuscle

Paper

Thursday, July 31

Clinical RheumatologyJul 31

The impact of aging and glucocorticoid use on physical function of older rheumatoid arthritis in remission: analysis of a National Database of Rheumatic Disease in Japan

Cohort study of 2,078 peopleRheumatoid arthritis

Paper

Wednesday, July 30

BMC Public HealthJul 30

Associations between sleep duration trajectories and physical dysfunction among middle-aged and older Chinese adults

Cohort study of 7,157 peoplePopulations

Paper

Tuesday, July 29

Frontiers in NeurologyJul 29

Association between frailty trajectories and stroke incidence among Chinese older adults: evidence from CHARLS 2011-2015

Cohort study of 8,049 peopleStroke

Paper