In an observational study of 1,110 people, living in more deprived areas was associated with lower cognitive scores and more amyloid build-up in unimpaired brains.In an observational study of 1,110 people, living in more deprived areas was associated with lower cognitive scores and more amyloid build-up in unimpaired brains.
A two-year randomised trial in 1,260 older adults at risk of dementia found no clear evidence that starting blood markers altered cognitive benefits.A two-year randomised trial in 1,260 older adults at risk of dementia found no clear evidence that starting blood markers altered cognitive benefits.
In PET scans of 77 patients with isolated REM sleep behavior disorder, quantitative dopamine markers showed intermediate loss and predicted phenoconversion toward…In PET scans of 77 patients with isolated REM sleep behavior disorder, quantitative dopamine markers showed intermediate loss and predicted phenoconversion toward Parkinson's disease.
Assays predicted amyloid-beta positivity with AUCs of 0.929 to 0.952, while simulated pTau217 screening cut amyloid PET scans by over 60%.Assays predicted amyloid-beta positivity with AUCs of 0.929 to 0.952, while simulated pTau217 screening cut amyloid PET scans by over 60%.