Percentage of vacuolated nucleus pulposus cells

Age is associated with percentage of vacuolated nucleus pulposus cells in zebrafish.

“With age, the percentage of vacuolated NP cells decreases, whereas that of non-vacuolated NP cells increases, as in mammals.”

Animalsnucleus pulposus

Characterization of zebrafish nucleus pulposus in development and aging: A fish model for probing human intervertebral disc degeneration and regeneration

bioRxiv (Cold Spring Harbor Laboratory)·21 Oct 2025Preprint