Percentage of non-vacuolated nucleus pulposus cells

Age is associated with percentage of non-vacuolated nucleus pulposus cells in zebrafish.

“With age, the percentage of vacuolated NP cells decreases, whereas that of non-vacuolated NP cells increases, as in mammals.”

Animalsnucleus pulposus

Characterization of zebrafish nucleus pulposus in development and aging: A fish model for probing human intervertebral disc degeneration and regeneration

bioRxiv (Cold Spring Harbor Laboratory)·21 Oct 2025Preprint