Fibrotic nucleus pulposus center span to nucleus pulposus diameter ratio

Age has no effect on fibrotic nucleus pulposus center span to nucleus pulposus diameter ratio in zebrafish (Largely constant at 50% regardless of age).

“Notably, the ratio of the span of the fibrotic NP center to NP diameter remains largely constant at 50% regardless of age”

Animalsnucleus pulposus

Characterization of zebrafish nucleus pulposus in development and aging: A fish model for probing human intervertebral disc degeneration and regeneration

bioRxiv (Cold Spring Harbor Laboratory)·21 Oct 2025Preprint