p75NTR
2 papers1 finding
- Cells2
Upstream
1IGF1R
upin mouse cells1
1 study
IGF1R
upin mouse cells1
IGF1R increases p75NTR in mouse cells.
“insulin-like growth factor-1 receptor (IGF1-R), the common regulator of lifespan and age-related events in many different organisms, is responsible for the TrkA-to-p75(NTR) switch”
Cellsin human neuroblastoma cell lines and mouse primary neurons
An aging pathway controls the TrkA to p75NTR receptor switch and amyloid beta-peptide generation
The EMBO journal13 Apr 2006
Latest
3 in 12 monthsJournal of Endocrinological Investigation
Caloric restriction attenuates oxidative and inflammatory markers of aging, while compromising germinative epithelium homeostasis in the rat aged testis
Experiments in 14 ratsDietary restriction
Journal of the American Veterinary Medical Association
Dysmetabolism of the nerve growth factor pathway in the aging brain plays a pivotal role in cognitive decline
ReviewMechanisms
bioRxiv
BDNF receptor balance gates AgRP-to-PVH fiber density and stimulation evoked feeding across caloric states
Preprint: experiments in miceBDNF signalling
International Journal of Molecular Sciences
Molecular Adaptations of BDNF/NT-4 Neurotrophic and Muscarinic Pathways in Ageing Neuromuscular Synapses
Experiments in animalsMechanisms
Frontiers in Molecular Neuroscience
Cholinergic neurodegeneration and cholesterol metabolism dysregulation by constitutive p75NTR signaling in the p75exonIII-KO mice
Experiments in animalsMechanisms
FASEB Journal
Aging inverts the effects of p75NTR -modulated mTOR manipulation on hippocampal neuron synaptic plasticity in male mice
Experiments in animalsMechanisms
Ageing Research Reviews
Fading memories in aging and neurodegeneration: Is p75 neurotrophin receptor a culprit?
ReviewMechanisms
Experimental Gerontology
Adaptation to partial urethral obstruction in healthy aging LOU rats and the role of nerve growth factor signaling pathway in the bladder
Experiments in animalsMechanisms