Journal of Molecular Histology·May 26Aucubin and Tanshinol from Bu-Shen-Huo-Xue-Fang (BSHXF) improve intervertebral disc degeneration through affecting nucleus pulposus cellExperiments in ratsIntervertebral disc degenerationPaper
Bone Research·Apr 14Dasatinib and quercetin senolytic treatment delays early onset intervertebral disc degeneration in SM/J miceExperiments in miceSenolyticsPaper
Research Square·Jul 1Dasatinib and quercetin senolytic treatment delays early onset intervertebral disc degeneration in SM/J micePreprint: experiments in miceSenolyticsPaper
Biochemical and Biophysical Research Communications·Feb 21Aged mice overexpressing cellular repressor of E1A-stimulated genes 1 in adipose tissues exhibited increased liposarcoma incidence and shortened lifespanExperiments in miceMechanismsPaper
Genes to Cells·Sep 17Elimination of physiological senescent cutaneous cells in a novel p16-dependent senolytic mouse model impacts lipid metabolism in skin agingExperiments in miceCellular senescencePaper
International Journal of Molecular Sciences·May 11Microcephaly Gene Mcph1 Deficiency Induces p19ARF-Dependent Cell Cycle Arrest and SenescenceExperiments in miceCell cycle regulationPaper
Experimental Neurology·Feb 8The cellular senescence response and neuroinflammation in juvenile mice following controlled cortical impact and repetitive mild traumatic brain injuryExperiments in miceDNA damage responsePaper
The Journal of Endocrinology·Aug 11Quercetin improves white adipose tissue redox homeostasis in ovariectomized ratsExperiments in ratsQuercetinPaper
Biomaterials Science·May 9Anti-aging biomaterial sturgeon chondroitin sulfate upregulating anti-oxidant and SIRT-1/c-fos gene expression to reprogram stem cell senescence and prolong longevityExperiments in miceInterventionsPaper
Scientific Reports·Jan 29Immortalized murine tenocyte cells: a novel and innovative tool for tendon researchExperiments in mouse cellsAI & dataPaper
Physiological Research·Aug 31Antisenescence effect of REAC biomodulation to counteract the evolution of myelodysplastic syndromeExperiments in human cellsInterventionsPaper
Cells·Feb 16Dynamic Spatiotemporal Expression Pattern of the Senescence-Associated Factor p16Ink4a in Development and AgingExperiments in miceCellular senescencePaper
European Journal of Pharmacology·Oct 25Anti-aging and anti-oxidant activities of murine short interspersed nuclear element antisense RNAExperiments in miceInterventionsPaper
Molecular Carcinogenesis·Sep 18RAS induced senescence of skin keratinocytes is mediated through Rho-associated protein kinase (ROCK)Experiments in miceCellular senescencePaper
Nature Communications·Sep 3Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in miceExperiments in miceSenolyticsPaper
Clinical Science·Jul 29Brahma-related gene-1 promotes tubular senescence and renal fibrosis through Wnt/β-catenin/autophagy axisExperiments in miceWnt/β-catenin signalingPaper
Biomolecules·Sep 26Emerging Roles for the INK4a/ARF (CDKN2A) Locus in Adipose Tissue: Implications for Obesity and Type 2 DiabetesReviewMechanismsPaper
Biomolecules·Mar 21p19Arf Exacerbates Cigarette Smoke-Induced Pulmonary DysfunctionExperiments in miceLung diseasePaper
Genes & Development·Mar 7The senotherapeutic drug ABT-737 disrupts aberrant p21 expression to restore liver regeneration in adult miceExperiments in miceInterventionsPaper
PNAS·Dec 11A cis-element within the ARF locus mediates repression of p16INK4A expression via long-range chromatin interactionsExperiments in human cellsEpigenetic regulation of gene expressionPaper
bioRxiv·Sep 5Senolytic treatment targets aberrant p21-expression to restore liver regeneration in adult micePreprint: experiments in miceSenolyticsPaper
Aging Cell·Aug 7Long-term repopulation of aged bone marrow stem cells using young Sca-1 cells promotes aged heart rejuvenationExperiments in miceInterventionsPaper
Matrix Biology·Feb 28p16Ink4a deletion in cells of the intervertebral disc affects their matrix homeostasis and senescence associated secretory phenotype without altering onset of senescenceExperiments in miceSenescence-associated secretory phenotype (SASP)Paper
Aging Cell·Jul 31Elimination of p19ARF -expressing cells protects against pulmonary emphysema in miceExperiments in miceLungPaper
Nephrology, Dialysis, Transplantation·Mar 10Mechanisms and consequences of oxidant-induced renal preconditioning: an Nrf2-dependent, P21-independent, anti-senescence pathwayExperiments in miceNRF2–KEAP1 antioxidant responsePaper
Journal of the American Society of Nephrology·Feb 15Wnt9a Promotes Renal Fibrosis by Accelerating Cellular Senescence in Tubular Epithelial CellsExperiments in miceCellular senescencePaper
Molecular and Cellular Endocrinology·Jun 28Oncogene-induced senescence and its evasion in a mouse model of thyroid neoplasiaExperiments in miceCellular senescencePaper
FEBS Open Bio·Jun 9Activation of Wnt/β-catenin signaling by lithium chloride attenuates d-galactose-induced neurodegeneration in the auditory cortex of a rat model of agingExperiments in ratsInterventionsPaper
Journal of Neuropathology and Experimental Neurology·Mar 25Cellular Senescence in Mouse Hippocampus After Irradiation and the Role of p53 and p21Experiments in miceCellular senescencePaper
Methods in Molecular Biology·Nov 5Detection of Oncogene-Induced Senescence In VivoStudy protocolCellular senescencePaper