The Journal of Investigative Dermatology·Oct 12Elevated ΔNp63α Levels Facilitate Epidermal and Biliary Oncogenic TransformationExperiments in miceMechanismsPaper
Scientific Reports·Sep 24SENP1 Is a Crucial Regulator for Cell Senescence through DeSUMOylation of Bmi1Experiments in mouse cellsCellular senescencePaper
JCI Insight·Aug 4Elimination of p19ARF-expressing cells enhances pulmonary function in miceExperiments in miceLungPaper
The Journal of Biological Chemistry·Mar 11Different Roles of Negative and Positive Components of the Circadian Clock in Oncogene-induced Neoplastic TransformationExperiments in mouse cellsCircadian clockPaper
Cancer Research·Jan 14Radiation-Induced Loss of Salivary Gland Function Is Driven by Cellular Senescence and Prevented by IL6 ModulationExperiments in miceInterventionsPaper
Aging·Jul 1Immortalization of MEF is characterized by the deregulation of specific miRNAs with potential tumor suppressor activityExperiments in mouse cellsMechanismsPaper
Cell·Nov 14Telomerase reverse transcriptase delays aging in cancer-resistant miceExperiments in miceInterventionsPaper
Cell·Oct 17Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf ExpressionExperiments in miceStem cell maintenancePaper
Circulation Research·Jan 15Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpressionExperiments in miceMechanismsPaper
Nature Cell Biology·Mar 1p16INK4A and p19ARF act in overlapping pathways in cellular immortalizationExperiments in mouse cellsCDKN2APaper
Nature·Nov 5Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cellsExperiments in human cellsTelomerase and telomere maintenancePaper
Oncogene·Jul 10Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and agingExperiments in miceCDKN2APaper