Papers on osteogenic differentiation

702 papers45 new in 30 days

Saturday, October 31

Cell Death & DiseaseOct 31

Virus-based delivery eased obesity or osteoporosis in mice

Virus-based supplementation of a stem-cell regulator eased obesity, osteoporosis or both across three mouse models.Virus-based supplementation of a stem-cell regulator eased obesity, osteoporosis or both across three mouse models.

Mouse studyOsteoporosis

Paper

Journal of Advanced ResearchOct 31

Estrogen helps mouse stem cells become bone-forming cells

Experiments in mouse bone marrow stem cells identified a protein pathway through which estrogen promoted the splitting of mitochondria, the cells’ energy-producing…Experiments in mouse bone marrow stem cells identified a protein pathway through which estrogen promoted the splitting of mitochondria, the cells’ energy-producing structures.

Animal cell studyBones and joints

Paper

Biochemical PharmacologyOct 31

Raising a protein eased signs of osteoporosis in mice

Experiments in mice whose ovaries had been removed found that increasing a mitochondrial protein eased signs of osteoporosis.Experiments in mice whose ovaries had been removed found that increasing a mitochondrial protein eased signs of osteoporosis.

Mouse studyPostmenopausal osteoporosis

Paper

Friday, October 30

Chinese Journal of Endocrinology and MetabolismOct 30

Mechanism of mechanical exercise in improving osteoporosis in ovariectomized mice by promoting osteogenic differentiation of bone marrow mesenchymal stem cells

Experiments in miceTreadmill exercise

Paper

Journal of EthnopharmacologyOct 30

Salidroside reduced bone loss in rats after ovary removal

High-dose salidroside increased bone volume fraction—the share of a measured volume occupied by bone—from 9.8% to 36.4% in rats.High-dose salidroside increased bone volume fraction—the share of a measured volume occupied by bone—from 9.8% to 36.4% in rats.

Rat studyBones and joints

Paper

Thursday, October 29

CellsOct 29

hiPSC Extract Attenuates Senescence-Associated Phenotypes in AB-MSCs In Vitro

Experiments in human cellsInterventions

Paper

BioengineeringOct 29

CCL2 Facilitates Osteoclastogenesis and Osteogenesis in Both Young and Aged Female Murine MSC–Macrophage Co-Cultures

Experiments in mouse cellsMechanisms

Paper

Frontiers in Cardiovascular MedicineOct 29

Lipoprotein(a) in calcific aortic stenosis: mechanistic insights, clinical evidence, and emerging therapies

ReviewMechanisms

Paper

Biomaterials ScienceOct 29

Stem cell-delivery hydrogels with shear-thinning injectability promote bone healing in distraction osteogenesis

Experiments in ratsBones and joints

Paper

Frontiers in MedicineOct 29

Sinus tarsi adipose tissue as a neuro-adipose niche in progressive collapsing foot deformity: neural innervation and stem cell properties

Representative H&E-stained sections of adipose tissue from subjects stratified by age (<18 and ≥18 years) and sex (females, F; males, M).

Cross-sectional study of 20 peopleMechanisms

Paper

Biomolecules & TherapeuticsOct 29

Adenine Promotes Osteogenic Differentiation and Suppresses Osteoclastogenesis

Experiments in mouse cellsInterventions

Paper

Materials Today BioOct 29

Injectable gel improved bone repair in rats

An animal experiment found improved bone volume, mineral density and blood vessel formation in rat thighbone defects after delivery of engineered cell-released particles.An animal experiment found improved bone volume, mineral density and blood vessel formation in rat thighbone defects after delivery of engineered cell-released particles.

Rat studyBones and joints

Paper

Wednesday, October 28

Advanced ScienceOct 28

Protein helps bone marrow stem cells develop into bone cells

Experiments in bone marrow stem cells linked the protein to mitochondrial maintenance and signals that support blood vessel formation.Experiments in bone marrow stem cells linked the protein to mitochondrial maintenance and signals that support blood vessel formation.

Animal cell studyBones and joints

Paper

Nature AgingOct 28

Statin use linked to slower bone density loss after menopause

An observational analysis linked statin use to slower annual declines in bone mineral density among postmenopausal women.An observational analysis linked statin use to slower annual declines in bone mineral density among postmenopausal women.

Cohort · 169 peopleStatins

Paper

Research SquareOct 28

Deleting an immune-related gene eased bone loss in female mice

An experiment compared female mice with and without an immune-regulating gene after ovary removal, finding higher bone density in mice without it.An experiment compared female mice with and without an immune-regulating gene after ovary removal, finding higher bone density in mice without it.

Crlf2 is highly expressed in osteoporosis samples and osteoclasts, and is lowly expressed in osteoblasts.

Preprint: mouse studyBones and joints

Paper

Cellular SignallingOct 28

Mechanistic study on the promotion of osteogenic differentiation in osteoporotic rats by moxibustion via regulation of BMSCs-derived exosomal miR-27a-3p-mediated mitophagy

Experiments in ratsBones and joints

Paper

BiomoleculesOct 28

A VEGF/BMP-6-Functionalized PLGA Scaffold Combined with Mesenchymal Stem Cells Promotes Bone Regeneration in a Chicken Femoral Defect Model

Experiments in chickensMesenchymal stem cells

Paper

Tuesday, October 27

AntioxidantsOct 27

Formononetin Protects Osteoblasts Against Oxidative Stress and Attenuates Ovariectomy-Induced Bone Loss in Association with MAPK/AP-1 and NRF2 Signaling

FMN attenuates OVX-induced trabecular bone loss and systemic oxidative stress in mice.

Experiments in miceBone loss

Paper

International Journal of Molecular SciencesOct 27

Directional Muscle-to-Bone Crosstalk via the Muscle Secretome: A Systematic Review

Flowchart of articles included in the systematic review.

Systematic review of animal and cell studiesBones and joints

Paper

Monday, October 26

ESC Congress 2026 AbstractOct 26

Semaglutide attenuates diabetic vascular calcification by enhancing autophagy and lysosomal function via targeting CPNE1

Experiments in miceSemaglutide

Paper

Advanced ScienceOct 26

Lithium nanowires accelerate bone repair in an animal model

In an aged jaw defect model, the material reduced local iron accumulation, alleviated immune cell aging, and accelerated bone regeneration.In an aged jaw defect model, the material reduced local iron accumulation, alleviated immune cell aging, and accelerated bone regeneration.

Mouse studyBones and joints

Paper

ESC Congress 2026 AbstractOct 26

Hsp90α attenuates calcific aortic valve disease by upregulation HIF-1α and suppressing VIC osteogenesis

Experiments in human cellsMechanisms

Paper

Sunday, October 25

Materials Today BioOct 25

Targeted RNA delivery alleviates bone loss in mice

In a mouse model of osteoporosis caused by ovary removal, bone-targeted engineered vesicles preserved bone structure and reduced bone-breakdown activity without causing…In a mouse model of osteoporosis caused by ovary removal, bone-targeted engineered vesicles preserved bone structure and reduced bone-breakdown activity without causing systemic toxicity.

Mouse studyBones and joints

Paper

Regenerative TherapyOct 25

Engineered bone-targeting particles reduced bone loss in mice

Weekly doses of particles carrying instructions for making the bone-building drug teriparatide improved spongy bone structure in a mouse model of osteoporosis.Weekly doses of particles carrying instructions for making the bone-building drug teriparatide improved spongy bone structure in a mouse model of osteoporosis.