Older hearts
3 findings
Effects
3Long-chain fatty acids
upin humans1
1 study
Long-chain fatty acids
upin humans1
Older hearts increase long-chain fatty acids in humans.
“along with an increase in long-chain fatty acids.”
Humansheart
The Human Cardiac "Age-OME": Age-Specific Changes in Myocardial Molecular Expression
Aging cell7 Sep 2025
Contractile apparatus
downin humans1
1 study
Contractile apparatus
downin humans1
Older hearts decrease contractile apparatus in humans.
“downregulation of proteins involved in calcium signalling and the contractile apparatus.”
Humansheart
The Human Cardiac "Age-OME": Age-Specific Changes in Myocardial Molecular Expression
Aging cell7 Sep 2025
calcium signaling pathway
downin humans1
1 study
calcium signaling pathway
downin humans1
Older hearts decrease calcium signaling pathway in humans.
“In older hearts, we observed a downregulation of proteins involved in calcium signalling and the contractile apparatus.”
Humansheart
The Human Cardiac "Age-OME": Age-Specific Changes in Myocardial Molecular Expression
Aging cell7 Sep 2025
Latest
4 in 12 monthsRomanian Journal of Internal Medicine
Polypharmacy and Potentially Inappropriate Medications: Cognitive Consequences in Older Heart Failure Outpatients
Cross-sectional study of 107 peopleHeart failure
JACC Asia
Adverse Events and ABC Pathway Adherence Across AF Clinical Phenotypes: APHRS-AF Registry Cluster Analysis Study
Cohort study of 3,468 peoplePopulations
Experimental Gerontology
Metabolomic biomarkers enhance 10-year mortality risk calibration and clinical utility in older heart failure patients: A UK Biobank study
Cohort study of 1,104 peopleHeart failure
AHA Scientific Sessions 2025 Abstract
Sodium-Glucose Cotransporter-2 Inhibitor Use Is Associated with Improved Cognitive Outcomes in Older Heart Failure Patients: A Comparative Analysis Using Real-World Clinical Data
Cohort study of 50,188 peopleSGLT2 inhibitors
Aging Cell
The Human Cardiac "Age-OME": Age-Specific Changes in Myocardial Molecular Expression
Cross-sectional study in peopleMechanisms