Cell Death & Disease·Mar 29The Sirt2-Nur77 axis regulates muscle stem cell quiescence and senescence via epigenetic-metabolic synergyExperiments in miceCellular senescencePaper
Journal of Agricultural and Food Chemistry·Mar 16Urolithin A Attenuates Aging-Induced Liver Injury by Inhibiting Nur77 Ubiquitination and DegradationExperiments in miceUrolithin APaper
FASEB Journal·Jan 22Nuclear Receptor Nur77: A Key Factor and Potential Therapeutic Target in the Aging Regulatory NetworkReviewMechanismsPaper
Redox Biology·Jan 19Triclosan exacerbates post-myocardial infarction injury via Nur77 ubiquitination: Linking NTRK2/PGC-1α-mediated mitochondrial dysfunction to senescence and ferroptosisExperiments in miceFerroptosisPaper
Advances in Experimental Medicine and Biology·Feb 11Potential Role of NUR77 in the Aging Retinal Pigment Epithelium and Age-Related Macular DegenerationReviewEyePaper
Reproductive Biology and Endocrinology·Jul 24Nur77 improves ovarian function in reproductive aging mice by activating mitophagy and inhibiting apoptosisExperiments in miceMitophagyPaper
Histology and Histopathology·May 1Natural products and synthetic analogs as selective orphan nuclear receptor 4A (NR4A) modulatorsReviewInterventionsPaper
European Journal of Pharmacology·Jan 2Nur77 alleviates cardiac fibrosis by upregulating GSK-3β transcription during agingExperiments in miceMechanismsPaper
British Journal of Pharmacology·Jun 2Emodin promotes hepatic stellate cell senescence and alleviates liver fibrosis via a nuclear receptor (Nur77)-mediated epigenetic regulation of glutaminase 1Experiments in miceLiver fibrosisPaper
Aging Cell·Mar 7Oxidative stress impairs the Nur77-Sirt1 axis resulting in a decline in organism homeostasis during agingExperiments in miceSirtuin signalingPaper
Journal of Cellular and Molecular Medicine·Feb 20Nur77 Prevents Osteoporosis by Inhibiting the NF-κB Signalling Pathway and Osteoclast DifferentiationExperiments in miceBones and jointsPaper
FASEB Journal·Jan 1Nur77 ameliorates age-related renal tubulointerstitial fibrosis by suppressing the TGF-β/Smads signaling pathwayExperiments in miceTGF-β signalingPaper
Biogerontology·May 24Sexual dimorphism in rat thymic involution: a correlation with thymic oxidative status and inflammationExperiments in ratsInflammationPaper
Hormone Molecular Biology and Clinical Investigation·Jan 8Practical prospects for boosting hepatic production of the "pro-longevity" hormone FGF21ReviewInterventionsPaper