Number of aged organs

Number of aged organs are associated with mortality in humans (2–4 aged organs: HR 2.3; 5–7: HR 4.5; 8+: HR 8.3).

“Accrual of aged organs progressively increased mortality risk (2-4 aged organs, HR = 2.3; 5-7 aged organs, HR = 4.5; 8+ aged organs, HR = 8.3)”

Humans17 years' follow-upn = 44,498

Plasma proteomics links brain and immune system aging with healthspan and longevity

Nature medicine·9 Jul 2025