Nicotinamide
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53bioRxivAnimalsPreprint
Nicotinamide riboside improves parasite control in mice
In mice infected with Trypanosoma cruzi, treatment with the NAD+ precursor improved CD8+ T-cell function and reduced parasite burden in blood and…In mice infected with Trypanosoma cruzi, treatment with the NAD+ precursor improved CD8+ T-cell function and reduced parasite burden in blood and skeletal muscle.
bioRxivModel organismsPreprint
Suppressing neuronal dENL/AF9 shifts metabolic and energetic profiles in aged flies
Multi-omics profiling in Drosophila links chromatin regulation to increased ATP, higher NAD-to-NADH ratios, and altered lipid metabolism in aged…Multi-omics profiling in Drosophila links chromatin regulation to increased ATP, higher NAD-to-NADH ratios, and altered lipid metabolism in aged heads.
Frontiers in BioscienceCells
Mechanism of the NAMPT-SIRT2-Lactate Axis in Senescence of Human Nucleus Pulposus Cells
Expert Opinion on Therapeutic TargetsReview
Sirtuin signaling as therapeutic targets of immunosenescence
Clinical Interventions in AgingReview
Therapeutic Targeting of Inflammaging and Emerging Strategies for Managing Age-Related Multimorbidity: A Narrative Review
Journal of Aging ResearchCells
β-Nicotinamide Mononucleotide Inhibits Cellular Senescence in Mouse C2C12 Skeletal Muscle Cells
Research SquareAnimalsPreprint
Long-term NMN treatment increases lifespan and healthspan in mice in a sex dependent manner
Frontiers in Sports and Active LivingReview