NFE2L2

1 paper

Animals1

Latest

6 in 12 months

Bioorganic Chemistry1 Oct

Selenylated Physalis pubescens polysaccharide extends lifespan and activates Nrf2/HO-1-mediated antioxidant defense: structural elucidation and multi-target mechanism

Experiments in fliesInterventions

Research Square25 Sep

Multiomics reveals a resilient subcutaneous adipose tissue phenotype in extreme human longevity

Preprint: cross-sectional study in peopleAI & data

Nature Genetics13 Sep

Cancer treatment alters mutant selection in normal esophagus

Cohort study of 70 peopleInterventions

bioRxiv30 Mar

A decline in skeletal muscle NOX4 abrogates adaptive homeostasis and exacerbates ageing

Preprint: experiments in miceMuscle

Computational and Structural Biotechnology Journal1 Mar

Integrated Multi-Tissue Transcriptomics Reveals Antagonistic Pleiotropy in Aging and Alzheimer's Disease

Computational studyMechanisms

Free Radical Biology & Medicine16 Jan

NRF2 at the crossroads of Parkinson's disease and aging: Mechanistic insights and translational perspectives

ReviewNRF2–KEAP1 antioxidant response

Frontiers in Neuroscience5 Jun

Expression and potential regulatory mechanism of cellular senescence-related genes in Alzheimer's disease based on single-cell and bulk RNA datasets

Computational studyMechanisms

Gene22 May

Genetic predictors of longevity and survival in cellular homeostasis genes: A case-control study

Study in peoplePopulations

Neuropharmacology30 Apr

Sirtuins modulators mitigate hypoxia-induced cell death due to changes in histone 3 acetylation, and mitochondrial function, dynamics, and content

Experiments in cellsMechanisms

Biochimica et Biophysica Acta Molecular Cell Research26 Apr

Deletion of Nrf1α exacerbates oxidative stress-induced cellular senescence by disrupting cell homeostasis

Experiments in cellsMechanisms