Selenylated Physalis pubescens polysaccharide extends lifespan and activates Nrf2/HO-1-mediated antioxidant defense: structural elucidation and multi-target mechanism
- Physalis pubescens polysaccharides
- NRF2–KEAP1 antioxidant response
- Oxidative stress and ROS signalling
- Ho
- NFE2L2
- SOD1
- STAT3
- cnc
- Malondialdehyde
- Superoxide dismutase
- Total antioxidant capacity
- Drosophila melanogaster
The paper
Selenylated Physalis pubescens polysaccharide extends lifespan and activates Nrf2/HO-1-mediated antioxidant defense: structural elucidation and multi-target mechanism
Liang H, Tan Y, Wang Z et al.
Bioorganic Chemistry · 23 Sep 2026