New York Heart Association Functional Classification

There are 9 papers on New York Heart Association Functional Classification in aging research: 2 trials and 7 observational studies in people.

Biomarker

9 papers study it4 more mention it3 findings

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“there was no statistically significant difference in improvement in NYHA class between the 2 groups at 1 year (odds ratio 1.07, 95% CI 0.85 to 1.25), p = 0.526).”
Long-Term Survival and Quality of Life Following Transcatheter Aortic Valve Replacement in NonagenariansThe American journal of cardiology2023doi:10.1016/j.amjcard.2023.12.031
  • Human trial2
  • Humans7

Associations

3

In-hospital mortality

upin humans1

1 study
  1. New York Heart Association Functional Classification is associated with in-hospital mortality in humans (surgical patients).

    “Higher NYHA class (III-IV) was significantly associated with an increased incidence of intraoperative arrhythmia (p = 0.007) and in-hospital mortality (p = 0.029).”

    Humanssurgical patients

    B54-30 Functional Capacity as a Predictor of Intraoperative Arrhythmia and Mortality in Surgical Patients Aged Ninety Years and Older

    American Journal of Respiratory and Critical Care Medicine

Intraoperative arrhythmia

upin humans1

1 study
  1. New York Heart Association Functional Classification is associated with intraoperative arrhythmia in humans (surgical patients).

    “Higher NYHA class (III-IV) was significantly associated with an increased incidence of intraoperative arrhythmia (p = 0.007)”

    Humanssurgical patients

    B54-30 Functional Capacity as a Predictor of Intraoperative Arrhythmia and Mortality in Surgical Patients Aged Ninety Years and Older

    American Journal of Respiratory and Critical Care Medicine

Nonagenarian age

no changein humans1OR 1.07

1 study
  1. Nonagenarian age is associated with New York Heart Association Functional Classification in humans (severe aortic stenosis) (OR 1.07, 95% CI 0.85 to 1.25).

    “there was no statistically significant difference in improvement in NYHA class between the 2 groups at 1 year (odds ratio 1.07, 95% CI 0.85 to 1.25), p = 0.526).”

    Humanssevere aortic stenosis1 yearn = 6,896

    Long-Term Survival and Quality of Life Following Transcatheter Aortic Valve Replacement in Nonagenarians

    The American journal of cardiology

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Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 1May 2026: 1Jun 2026: 0Jul 2026: 1Aug 2026: 2Sep 2026: 0Oct 2026: 0Nov 2026: 05 papers in 12 months

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