Neuroligin-derived peptides

1. Cognitive impairment increases neuroligin-derived peptides in humans.

   “levels of specific NLGN peptides were significantly elevated in CI compared to CN individuals.”

   Humanscognitively impaired vs cognitively normal individualsplasma

   Differences in blood levels of neuroligin-derived peptides in a cohort for early detection of Alzheimer's disease

   The journals of gerontology. Series A, Biological sciences and medical sciences·5 Feb 2026

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1. MAPT is associated with neuroligin-derived peptides in humans.

   “specific plasma phosphorylated tau peptides were significantly and positively correlated with selected NLGN-derived peptides in more advanced stages of cognitive decline.”

   Humansmore advanced stages of cognitive declineplasma

   Differences in blood levels of neuroligin-derived peptides in a cohort for early detection of Alzheimer's disease

   The journals of gerontology. Series A, Biological sciences and medical sciences·5 Feb 2026

More on MAPT