There are 6 papers on mTOR protein in aging research: 1 observational study in people, 5 in animals.
6 papers study it32 more mention it3 findings
1 new paper in 30 daysSee all 38 papers on mTOR protein
“the levels of miR-496 and mTOR protein were inversely correlated in Peripheral Blood Mononuclear Cells (PBMC)”
- Humans1
- Animals5
Interventions
1Metformin
downin mice1
1 study
Metformin
downin mice1
Metformin decreases mTOR protein in db/db mice.
“reduces the levels of the mTOR and p-mTOR proteins”
Animalsin db/db micekidney
Journal of medical systems
Upstream
1MIR496
downin human cells1
1 study
MIR496
downin human cells1
MIR496 decreases mTOR protein in human cells (miR-496 coexpression).
“miR-496 reduced the mTOR protein level in HeLa-K cells”
CellsmiR-496 coexpressionHeLa-K
microRNA-496 - A new, potentially aging-relevant regulator of mTOR
Cell cycle (Georgetown, Tex.)
Associations
1MIR496
downin humans1
1 study
MIR496
downin humans1
MIR496 is associated with mTOR protein in humans.
“the levels of miR-496 and mTOR protein were inversely correlated in Peripheral Blood Mononuclear Cells (PBMC)”
Humansperipheral blood mononuclear cell
microRNA-496 - A new, potentially aging-relevant regulator of mTOR
Cell cycle (Georgetown, Tex.)
Latest
4 papers in 12 monthsPharmacological Reports
Fast-acting antidepressant-like effects of ketamine in aged male rats
Experiments in ratsInterventions
Scientific Reports
Regulation of vitamin D system in skeletal muscle and resident myogenic stem cell during development, maturation, and ageing
Experiments in miceMuscle
Poultry Science
Melatonin regulates the ovarian function and enhances follicle growth in aging laying hens via activating the mammalian target of rapamycin pathway
Experiments in 60 chickensMelatonin
Journal of Medical Systems
Basic Research in Diabetic Nephropathy Health Care: A study of the Renoprotective Mechanism of Metformin
Experiments in miceMetformin
Scientific Reports
Premature recruitment of oocyte pool and increased mTOR activity in Fmr1 knockout mice and reversal of phenotype with rapamycin
Experiments in micemTOR signaling
Cell Cycle
microRNA-496 - A new, potentially aging-relevant regulator of mTOR
Study of 40 peoplemTOR signaling
Journal of Leukocyte Biology
Spermidine-mediated AMPK signaling pathway drives M2 macrophage polarization to promote the growth of vaginal cancer
Experiments in cellsAMPK signaling
Iranian Journal of Basic Medical Sciences
Protective effects and mechanism of chrysophanol against age-related osteoporosis in rats
Experiments in ratsOsteoporosis
bioRxiv
Canonical mTOR signaling supports complete fin regeneration
Preprint: experiments in animalsType I interferon signaling