There are 2 papers on MIR496 in aging research: 2 observational studies in people.
At a glance
The findings reach people, from one lab or study. 1 lab in 1 country.
“the levels of miR-496 and mTOR protein were inversely correlated in Peripheral Blood Mononuclear Cells (PBMC)”
None of its findings points the other way.
Cells and humans: a single group. Worms or flies and mice: nothing yet.
- 1 lab in 1 country
- Humans2
Effects
1mTOR protein
downin human cells1
1 study
mTOR protein
downin human cells1
MIR496 decreases mTOR protein in human cells (miR-496 coexpression).
“miR-496 reduced the mTOR protein level in HeLa-K cells”
CellsmiR-496 coexpressionHeLa-K
microRNA-496 - A new, potentially aging-relevant regulator of mTOR
Cell cycle (Georgetown, Tex.)
Associations
1mTOR protein
downin humans1
1 study
mTOR protein
downin humans1
MIR496 is associated with mTOR protein in humans.
“the levels of miR-496 and mTOR protein were inversely correlated in Peripheral Blood Mononuclear Cells (PBMC)”
Humansperipheral blood mononuclear cell
microRNA-496 - A new, potentially aging-relevant regulator of mTOR
Cell cycle (Georgetown, Tex.)
Latest
Endocrine Research
Age-associated increase of thyroid hormone receptor β gene promoter methylation coexists with decreased gene expression
Cross-sectional study in peopleDNA methylation
Cell Cycle
microRNA-496 - A new, potentially aging-relevant regulator of mTOR
Study of 40 peoplemTOR signaling