mtDNA copy number

1. Induced mesenchymal stem cell is associated with mtDNA copy number in human cells.

   “Reprogramming into iPSCs and subsequent differentiation into iMSCs were associated with an increase in mtDNA copy number”

   Cellscellular reprogramming into iPSCs and differentiation to iMSCs

   Characterization of the Mitochondrial Genome Landscape in MSCs, iPSCs and iMSCs from Osteoarthritis Patients and Healthy Donors · Genes · 11 Sep 2026

1. Osteoarthritis is associated with mtDNA copy number in human cells.

   “OA-derived MSCs exhibited a markedly increased heteroplasmic burden, followed by decrease in mtDNA copy number”

   Cellsbone marrow mesenchymal stem cell

   Characterization of the Mitochondrial Genome Landscape in MSCs, iPSCs and iMSCs from Osteoarthritis Patients and Healthy Donors · Genes · 11 Sep 2026

Osteoarthritis →