MRI markers

Biomarker

2 papers study it105 more mention it2 findings

Humans2

Associations

Within-person changes in cognitive functioning

upin humans1+17% within-person variance explained

1 study

MRI markers predict within-person changes in cognitive functioning in humans (Up to 17.2% of within-person variance explained).
“Variance decomposition showed MRI markers explained substantial between-person variance (up to 60.3%) but modest within-person changes (up to 17.2%) in cognitive functioning.”
HumansbrainUp to three waves, five years apartn = 450
Multimodal MRI prediction of cognitive functioning across the lifespan: separating between-person differences from within-person changes
bioRxiv (Cold Spring Harbor Laboratory)Mar 18, 2026Preprint

Between-person differences in cognitive functioning

upin humans1+60% between-person variance explained

1 study

MRI markers predict between-person differences in cognitive functioning in humans (Up to 60.3% of between-person variance explained).
“Variance decomposition showed MRI markers explained substantial between-person variance (up to 60.3%) but modest within-person changes (up to 17.2%) in cognitive functioning.”
HumansbrainUp to three waves, five years apartn = 450
Multimodal MRI prediction of cognitive functioning across the lifespan: separating between-person differences from within-person changes
bioRxiv (Cold Spring Harbor Laboratory)Mar 18, 2026Preprint

Funding

5 grants since 2018

National Institute on AgingUS$3.8mUniversity of Maryland, Baltimore CountyUS$76.4kAlzheimer's Association

Latest

41 papers in 12 months

Research SquareOct 17

Brain scan markers may track different processes after sleep loss

In a 429-person sleep intervention study, proposed brain-scan measures of waste clearance responded differently to restricted sleep and prolonged wakefulness.In a 429-person sleep intervention study, proposed brain-scan measures of waste clearance responded differently to restricted sleep and prolonged wakefulness.

Preprint: non-randomized trial · 429 peopleMechanisms

Paper

Frontiers in Aging NeuroscienceOct 2

Gait performance in cerebral small vessel disease: associations with cognitive and oculomotor function and exploratory mediation analyses

Case-control study in peopleCerebral small vessel disease

Paper

Neurology GeneticsOct 1

GLP-1 receptor agonists link to lower stroke and Alzheimer risk

A cross-ancestry Mendelian randomization study of up to 1,812,017 individuals linked genetically proxied GLP-1 receptor agonist exposure to reduced risk of stroke and…A cross-ancestry Mendelian randomization study of up to 1,812,017 individuals linked genetically proxied GLP-1 receptor agonist exposure to reduced risk of stroke and Alzheimer disease.

Mendelian randomization in peopleGLP-1 receptor agonists

Paper

bioRxivSep 29

DASH diet across adulthood links to better late-life brain health

In 892 older adults, brain measures mediated 12.3% and 12.5% of the links between DASH diet adherence and late-life verbal memory.In 892 older adults, brain measures mediated 12.3% and 12.5% of the links between DASH diet adherence and late-life verbal memory.

Preprint: cohort study of 892 peoplePopulations

Paper

NeuroImageSep 22