3 papers3 findings
Cognitive function
upin humans1
Functional connectivity predicts cognitive function in humans.
Humansfrontoparietal network intrinsic connectivity in people living with HIVbrainn = 39
Research Square19 Aug 2026Preprint
Gait speed
upin humans1
Functional connectivity predicts gait speed in humans.
Humansfrontoparietal network intrinsic connectivity in people living with HIVbrainn = 39
Research Square19 Aug 2026Preprint
Stressful life events
downin humans1
Stressful life events are associated with functional connectivity in humans.
Humanshealthy minds for life studybrainn = 426
Cognitive, affective & behavioral neuroscience7 Aug 2026
National Institute on AgingUS$799.8k
Joint Harmonization of Structural and Functional Connectivity and its Application in Aging and AD
National Institute on AgingMassachusetts General HospitalUS$134.7k2026–2028
The contribution of declines in functional connectivity to cognitive aging
National Institute on AgingUniversity of ArizonaUS$532.4k2016–2027
Development of Dynamic Resting State Functional Connectivity Machine Learning Framework for Dementia
National Institute on AgingUniversity of California, San FranciscoUS$132.7k2022–2027
During a navigation task, one brain connectivity pattern had an approximately 65% smaller range in 19 older adults than in 19 younger adults.During a navigation task, one brain connectivity pattern had an approximately 65% smaller range in 19 older adults than in 19 younger adults.
In 3-month-old and 18-month-old mice with experimental stroke, aged animals failed to regain somatomotor functional connectivity and behavioral performance.In 3-month-old and 18-month-old mice with experimental stroke, aged animals failed to regain somatomotor functional connectivity and behavioral performance.
Two human cohorts of 973 and 129 individuals revealed that aging and Alzheimer's disease disrupt separate, orthogonal functional communication axes across the brain.Two human cohorts of 973 and 129 individuals revealed that aging and Alzheimer's disease disrupt separate, orthogonal functional communication axes across the brain.
In 101 people with mild cognitive impairment, the model predicted conversion with an AUC of 0.72 and mirrored rates of brain atrophy and cognitive decline.In 101 people with mild cognitive impairment, the model predicted conversion with an AUC of 0.72 and mirrored rates of brain atrophy and cognitive decline.
In two human cohorts, Alzheimer's genetic risk predicted childhood ADHD, while an ADHD-related brain profile correlated with reproductive aging markers and poorer…In two human cohorts, Alzheimer's genetic risk predicted childhood ADHD, while an ADHD-related brain profile correlated with reproductive aging markers and poorer late-life cognition.
In cognitively unimpaired older adults, intermediate amyloid burden showed lower dopamine-transporter deviation scores than amyloid-positive status, with an adjusted…In cognitively unimpaired older adults, intermediate amyloid burden showed lower dopamine-transporter deviation scores than amyloid-positive status, with an adjusted difference of −0.582.