Mitochondrial respiratory chain activity
1 paper studies it5 more mention it1 finding
- Cells1
Interventions
1Glutaminolysis inhibitor
upin mice1
1 study
Glutaminolysis inhibitor
upin mice1
Glutaminolysis inhibitor improves mitochondrial respiratory chain activity in mice.
“Inhibition of glutaminolysis in progeria mice improves mitochondrial respiratory chain activity”
Animalsin progeria mice
Inhibition of glutaminolysis restores mitochondrial function in senescent stem cells
Cell reports
Latest
1 paper in 12 monthsCardiovascular Diabetology
Integrated adipose tissue transcriptomic and miRNA remodeling identifies molecular pathways associated with residual cardiovascular risk after weight loss
Non-randomized trial in 66 peopleCardiovascular disease
Journal of Controlled Release
Mitochondria-targeted NAD⁺/O₂ co-delivery interpenetrating network hydrogel for respiratory chain restoration and osteoarthritis therapy
Experiments in animalsOsteoarthritis
Mechanisms of Ageing and Development
ELN regulates cellular senescence: Emerging hypothesis for a non-canonical role
ReviewCellular senescence
Cell Reports
Inhibition of glutaminolysis restores mitochondrial function in senescent stem cells
Experiments in human cellsOxidative phosphorylation
Microbial Cell
Balanced CoQ₆ biosynthesis is required for lifespan and mitophagy in yeast
Experiments in cellsMechanisms