Mitochondrial permeability transition pore activity

Female increases mitochondrial permeability transition pore activity in mice.

“aged females exhibit heightened mitochondrial permeability transition pore (mPTP) activity”

Animalsaged micehippocampusfemales

Unraveling sex differences in age-related hippocampal decline: differential mitochondrial dysfunction, Lonp1-dependent mitochondrial proteostasis and mtROS production in aged C57BL/6 mice

Cell death & disease·30 Dec 2025