Mitochondrial fragmentation

Biomarker1 paper

Model organisms1

Latest

5

bioRxivModel organismsPreprint2 h

Disrupting protein entry delays signs of muscle aging in worms

Genetic experiments in worms found that disrupting a muscle protein’s entry into cell nuclei preserved gene activity for the machinery of contraction…Genetic experiments in worms found that disrupting a muscle protein’s entry into cell nuclei preserved gene activity for the machinery of contraction during aging.

Cell Death and DifferentiationAnimals24 Sep

Ubiquitination-mediated degradation of NLRX1 drives metabolic vulnerability and accelerates intervertebral disc degeneration

Oxidative phosphorylation

Nature CommunicationsModel organisms11 Sep

InsP3R signaling and actomyosin-dependent mitochondrial dynamics play essential roles in mitochondrial stress-induced longevity

Mitochondrial fission and fusion

Experimental GerontologyAnimals3 Sep

Age-related disruptions in ubiquitination and mitochondrial proteostasis are associated with neuronal compartment-specific mitochondrial changes

AntioxidantsModel organisms27 Aug

Mitochondrial Ca²⁺ Influx via MCU-1 Contributes to Oxidative Mitochondrial Defects in PDR-1/Parkin-Deficient Caenorhabditis elegans Body-Wall Muscle