Micro-computed tomography

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47 papers in 12 months

Research SquareOct 16

Riociguat Suppresses Osteoclastogenesis and Ovariectomy-Induced Bone Loss by Attenuating MAPK Signaling and PPARγ–PGC-1β Coupling

Preprint: experiments in miceBone loss

Paper

Acta Orthopaedica BelgicaOct 16

3D bioprinted porous PLLA implants with dual gene modified BMSCs for osteoarthritis cartilage repair

Experiments in animalsOsteoarthritis

Paper

European Journal of PharmacologyOct 15

Gut microbe products helped metformin protect bone in mice

Experiments in mice with ovaries removed linked the drug’s bone benefits to short-chain fatty acids, small molecules made by gut bacteria.Experiments in mice with ovaries removed linked the drug’s bone benefits to short-chain fatty acids, small molecules made by gut bacteria.

Mouse studyMetformin

Paper

Bone ReportsOct 14

Atractylenolide III attenuates age-related vertebral bone loss by suppressing macrophage inflammation and osteoclastogenesis

Experiments in miceBones and joints

Paper

Pharmaceutical BiologyOct 9

Honokiol promotes bone formation and fracture repair in mice

In mice with bone loss or fractures, honokiol promoted bone formation predominantly linked to sirtuin 3, while broader effects appeared only partly dependent on the…In mice with bone loss or fractures, honokiol promoted bone formation predominantly linked to sirtuin 3, while broader effects appeared only partly dependent on the enzyme.

Experiments in miceBones and joints

Paper

Journal of Orthopaedic TranslationOct 8

From biofabrication to preclinical translation: a systematic review of animal models for 3D-bioprinted hydrogel strategies in hyaline cartilage repair

Systematic review of animal and cell studiesBones and joints

Paper

bioRxivOct 6

Osteoporosis therapies affect bone cell spaces differently in mice

In a four-week mouse experiment, a bone-building hormone enlarged the spaces housing bone cells, while a drug that slows bone breakdown stabilized their local structure.In a four-week mouse experiment, a bone-building hormone enlarged the spaces housing bone cells, while a drug that slows bone breakdown stabilized their local structure.

Preprint: experiments in micePostmenopausal osteoporosis

Paper

Frontiers in BioscienceSep 30

Ergothioneine Attenuates Ovariectomy-Induced Bone Loss in Association With Reduced Oxidative Stress and Enhanced Type H Vessel-Related Angiogenesis

Experiments in 18 miceBones and joints

Paper

BoneSep 30

Beyond mean trabecular separation: decomposing metaphyseal marrow space into lower- and higher-diameter components

Experiments in animalsMechanisms

Paper

PharmaceuticsSep 28

Surface-Engineered Phytochemical Nanomedicines for Postmenopausal Osteoporosis: Skeletal Targeting, Imaging-Supported Evaluation, and Therapeutic Performance

ReviewPostmenopausal osteoporosis

Paper