Medin

2 papers study it4 more mention it2 findings

Associations

2

Hypertension

upin reviews1

1 study

Medin is associated with hypertension.
“Preclinical work showed that medin is associated with aging-related cerebral vascular dysfunction, vascular stiffening, hypertension, and. vascular amyloid β deposition.”
Review
Medin, a link between vascular pathology and dementia?
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and MetabolismOct 7, 2024

More on Hypertension

Dementia

upin humans1

1 study

Medin predicts dementia in humans.
“Recent literature revealed medin as biomarker for dementia in CSF, specifically of a vascular subtype.”
Reviewvascular subtype
Medin, a link between vascular pathology and dementia?
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and MetabolismOct 7, 2024

More on Dementia

Funding

2 grants since 2018

Veterans AffairsNational Institute on AgingUS$347.4k

Latest

1 paper in 12 months

bioRxivJul 8

Medin-Induced Pro-inflammatory and Prothrombotic Activation of Coronary Artery Endothelial Cells: A Potential Novel Mediator Linking Aging and Atherosclerosis

Preprint: study of 40 peopleInflammation

BiomoleculesAug 30

Aortic Stiffness and Alzheimer's Disease: The Medin Connection

ReviewMechanisms

Journal of Cerebral Blood Flow and MetabolismOct 7

Medin, a link between vascular pathology and dementia?

ReviewMechanisms

Aging CellNov 27

Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization

Experiments in human cellsCellular senescence

PNASSep 10

Medin aggregation causes cerebrovascular dysfunction in aging wild-type mice

Experiments in animalsMechanisms

Geriatrics & Gerontology InternationalAug 23

Age-associated proteomic alterations in human aortic media

Study in peopleMechanisms