Macrophage-like vascular smooth muscle cells

1. Caloric restriction decreases macrophage-like vascular smooth muscle cells in mice.

   “The presence of macrophage-like VSMCs and increased STING1 expression were confirmed in Ercc1Δ/- aortic tissue and were both reduced by DR.”

   Animalsin Ercc1Δ/- aortic tissueaorta

   Dietary Restriction Mitigates Vascular Aging, Modulates the cGAS-STING Pathway and Reverses Macrophage-Like VSMC Phenotypes in Progeroid DNA-Repair-Deficient Ercc1Δ /- Mice

   Aging cell·Apr 25, 2025

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