Lung function
Biomarker1 paper1 finding
- Humans1
Associations
1Microbiome composition
mixedin humans1
1 study
Microbiome composition
mixedin humans1
Microbiome composition is associated with lung function in humans.
Humansin prospective aging cohortrespiratory tract
The human oral and airway viral genome catalog from metagenomes enables virome characterization informing respiratory health · Med (New York, N.Y.) · 2 Sep 2026
Funding
National Heart, Lung, and Blood InstituteUS$758.2kNational Institute of Environmental Health SciencesUS$692k2 grants since 2023
Latest
37Aging in a Dish: Pulmonary Organoids as Models of Lung Aging
Most COPD is underdiagnosed and linked to higher mortality
In over 119,000 adults, 89.2% of COPD cases were underdiagnosed, which was associated with a 1.53 hazard ratio for mortality compared to having no…In over 119,000 adults, 89.2% of COPD cases were underdiagnosed, which was associated with a 1.53 hazard ratio for mortality compared to having no COPD.
Lung function declines in young adults in rural Uganda
FEV₁ declined by 10 mL per year across the cohort, and dropped 18 mL annually in individuals with normal baseline spirometry.FEV₁ declined by 10 mL per year across the cohort, and dropped 18 mL annually in individuals with normal baseline spirometry.
COPD and lung restriction affect many older African adults
In a study of 1,619 adults, overall COPD prevalence reached 16.1% and lung restriction reached 21.3%, with odds for both rising with older age.In a study of 1,619 adults, overall COPD prevalence reached 16.1% and lung restriction reached 21.3%, with odds for both rising with older age.
Peak oxygen uptake falls in older cyclists over nine years
In 82 older cyclists followed across nine years, peak oxygen consumption fell 19.7%, dropping from 44.1 to 35.4 ml·kg⁻¹·min⁻¹.In 82 older cyclists followed across nine years, peak oxygen consumption fell 19.7%, dropping from 44.1 to 35.4 ml·kg⁻¹·min⁻¹.
Age-linked immune endotypes are associated with COPD risk
In 89 adults, high- and moderate-inflammatory endotypes had adjusted odds ratios of 17.2 and 7.1 for COPD high-risk status versus a low-inflammatory…In 89 adults, high- and moderate-inflammatory endotypes had adjusted odds ratios of 17.2 and 7.1 for COPD high-risk status versus a low-inflammatory group.