Liver Aging Index

Liver Aging Index predicts mortality in humans (AUROC 0.764 in NHANES; 0.759 in VCTE-Prognosis).

“the LAI demonstrated strong discrimination for all-cause mortality (AUROC: 0.764 in NHANES; 0.759 in VCTE-Prognosis), outperforming chronological age (p < 0.05).”

HumansExternal validation in NHANES and VCTE-Prognosis; comparison with chronological ageliver

Liver Aging Index: A Noninvasive Score for Liver Biological Aging and Liver-Related Outcomes in Multicohorts

Aging cell·31 May 2026