Lithium

1. Tirzepatide increases lithium in humans (+0.08 ± 0.17 mmol/L (p = 0.030)).

   Humanslithium-treated bipolar disorder12 weeksn = 23

   Tirzepatide Initiation in Lithium-Treated Bipolar Disorder: Renal Biomarker Trajectories and Lithium Safety Signals Over 12 Months in a Real-World Cohort · Human psychopharmacology · 29 Sep 2026

Tirzepatide →