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Lipid droplet and cholesterol ester load

Biomarker

1 paper1 finding

  • Animals1

Upstream

1

PLA2G2F

downin human cells1

1 study

  1. PLA2G2F decreases lipid droplet and cholesterol ester load in human cells.

    “Neuronal PLA2G2F mediates intercellular signaling to decrease lipid droplet and cholesterol ester load in human induced pluripotent stem cell-derived microglia.”

    Cellsneuronal PLA2G2F-mediated intercellular signalinginduced pluripotent stem cell-derived microglia

    Boosting a secreted enzyme protected memory in aging mice

    Nature neuroscience15 Oct 2026

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Nature Neuroscience

Boosting a secreted enzyme protected memory in aging mice

Experiments in mice suggested that an enzyme released by nerve cells helps compensate for age-related brain changes and preserve memory.Experiments in mice suggested that an enzyme released by nerve cells helps compensate for age-related brain changes and preserve memory.

Experiments in miceMechanisms
Paper

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