LINE-1 RNA

5 papers

Humans4
Cells1

Latest

2 in 12 months

Aging Cell2 Jan

Systemic LINE-1 RNA in Plasma Extracellular Vesicles Drives Neuroinflammation and Cognitive Dysfunction via cGAS-STING Pathway in Aging

Study in peoplecGAS–STING signalling

medRxiv25 Dec

Association of LINE-1 RNA expressions in cell lines with longevity and reproductive lifespan

Preprint: cohort study in peopleMechanisms

eLife25 Sep

Steady-state neuron-predominant LINE-1 encoded ORF1p protein and LINE-1 RNA increase with aging in the mouse and human brain

Study in peopleMechanisms

eLife26 Aug

Steady-state neuron-predominant LINE-1 encoded ORF1p protein and LINE-1 RNA increase with aging in the mouse and human brain

Preprint: study in peopleMechanisms

eLife24 Jun

Steady-state neuron-predominant LINE-1 encoded ORF1p protein and LINE-1 RNA increase with aging in the mouse and human brain

Preprint: study in peopleMechanisms

eLife6 Sep

Steady-state neuron-predominant LINE-1 encoded ORF1p protein and LINE-1 RNA increase with aging in the mouse and human brain

Preprint: study in peopleMechanisms

PLOS Genetics7 Jun

An eQTL-based approach reveals candidate regulators of LINE-1 RNA levels in lymphoblastoid cells

Experiments in cellsMechanisms

bioRxiv30 Aug

An eQTL-based Approach Reveals Candidate Regulators of LINE-1 RNA Levels in Lymphoblastoid Cells

Preprint: experiments in cellsMechanisms

Science Translational Medicine10 Aug

LINE-1 RNA causes heterochromatin erosion and is a target for amelioration of senescent phenotypes in progeroid syndromes

Experiments in human cellsInterventions