LIBRA index

1. Low socioeconomic status increases LIBRA index in humans (B=0.53, 95% CI 0.15 to 0.92).

   “low vs high: B=0.53, 95%CI=0.15 to 0.92”

   Humansn = 1,048

   Education, socioeconomic status, modifiable dementia risk and cognitive performance in older adults at risk of cognitive decline: a cross‐sectional study of the FINGER‐NL trial

   AAIC 2025 abstract·23 Dec 2025

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1. LIBRA index impairs cognitive functioning in humans.

   “Higher LIBRA scores were consistently associated with lower cognitive functioning across adulthood.”

   Humansn = 149,948

   LIfestyle for BRAin health (LIBRA) and cognitive functioning from young to old adulthood: Results of the German National Cohort (NAKO)

   AAIC 2025 abstract·23 Dec 2025

1. LIBRA index is associated with cognitive resilience in humans (MD 0.04, 95% CI 0.02, 0.07).

   “Lower LIBRA risk scores at baseline, denoting reduced dementia risk, were linearly associated with higher CR Levels (mean difference [MD] for 1‐point lower in LIBRA=0.04; 95%CI=0.02,0.07)”

   Humans1-point lower in LIBRA71% femalesn = 585

   Associations of the LIfestyle for BRAin health index with Cognitive Resilience to neuropathology

   AAIC 2025 abstract·23 Dec 2025

1. Education is associated with LIBRA index in humans (B=2.01, 95% CI 1.54 to 2.48).

   “low vs high: B=2.01, 95%CI=1.54 to 2.48”

   Humansn = 1,048

   Education, socioeconomic status, modifiable dementia risk and cognitive performance in older adults at risk of cognitive decline: a cross‐sectional study of the FINGER‐NL trial

   AAIC 2025 abstract·23 Dec 2025

More on Education