LEAP-2/ghrelin ratio

1. Ampicillin + vancomycin + neomycin + metronidazole decreases LEAP-2/ghrelin ratio in rats.

   “Consequently, the LEAP-2/ghrelin ratio declined in the liver and showed a nonsignificant upward trend in WAT.”

   Animalsin aged male ratsliverone-weekmales

   Antibiotic exposure alters the LEAP-2/ghrelin axis and anti-inflammatory tone in aged male rat liver and adipose tissue

   Biogerontology·12 Dec 2025

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