LEAP-2

1. Ampicillin + vancomycin + neomycin + metronidazole decreases LEAP-2 in rats.

   “Antibiotic treatment lowered LEAP-2 in both liver and WAT.”

   Animalsin aged male ratsliver and white adipose tissueone-weekmales

   Antibiotic exposure alters the LEAP-2/ghrelin axis and anti-inflammatory tone in aged male rat liver and adipose tissue

   Biogerontology·12 Dec 2025

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