Aging Cell·Apr 14Ketone bodies: A double-edged sword for mammalian life spanExperiments in miceInterventionsPaper
bioRxiv·Mar 23Intermittent Fasting induced ketogenesis inhibits mouse epithelial ovarian tumors by promoting anti-tumor T cell responsePreprint: experiments in miceIntermittent fastingPaper
The Journal of Biological Chemistry·Feb 13Innate immune cell-intrinsic ketogenesis is dispensable for organismal metabolism and age-related inflammationExperiments in miceInflammationPaper
Clinical and Molecular Hepatology·Dec 15Eating, diet, and nutrition for the treatment of non-alcoholic fatty liver diseaseReviewMetabolic dysfunction-associated steatotic liver diseasePaper
Kidney and Dialysis·Nov 17The Pathophysiological Basis of Diabetic Kidney Protection by Inhibition of SGLT2 and SGLT1ReviewSGLT2 inhibitorsPaper
bioRxiv·Oct 7Ketone body metabolism declines with age in mice in a sex-dependent mannerPreprint: experiments in miceMechanismsPaper
PNAS·Sep 27Circadian clock controls rhythms in ketogenesis by interfering with PPARα transcriptional networkExperiments in miceInterventionsPaper
Life Metabolism·Aug 11The neonatal ketone body is important for primordial follicle pool formation and regulates ovarian ageing in miceExperiments in miceReproductive systemPaper
Frontiers in Nutrition·Aug 2Supplementation of Regular Diet With Medium-Chain Triglycerides for Procognitive Effects: A Narrative ReviewReviewInterventionsPaper
GeroScience·Jul 22Circulating cell-free DNA in health and disease - the relationship to health behaviours, ageing phenotypes and metabolomicsCross-sectional study of 5,385 peopleCell-free DNAPaper
Current Diabetes Reviews·May 14Low-Carbohydrate Ketogenic Diet for Improvement of Glycemic Control: Mechanism of Action of Ketosis and Beneficial EffectsReviewKetogenic dietPaper
Frontiers in Nutrition·Apr 19Short-Term Ketogenic Diet Induces a Molecular Response That Is Distinct From Dietary Protein RestrictionExperiments in miceKetogenic dietPaper
Aging Cell·Oct 31Dietary citrate supplementation enhances longevity, metabolic health, and memory performance through promoting ketogenesisExperiments in fliesInterventionsPaper
Journal of Cachexia, Sarcopenia and Muscle·Oct 20Is muscle and protein loss relevant in long-term fasting in healthy men? A prospective trial on physiological adaptationsNon-randomized trial in 16 peopleMusclePaper
Nature Metabolism·Oct 14Fasting-mimicking diet prevents high-fat diet effect on cardiometabolic risk and lifespanExperiments in miceDietary restrictionPaper
Endocrinology·Aug 1SGLT2 Inhibitors as Calorie Restriction Mimetics: Insights on Longevity Pathways and Age-Related DiseasesReviewmTOR inhibitorsPaper
eLife·Jun 22Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in miceExperiments in miceKetogenic dietPaper
Trends in Immunology·Apr 19Enemy or ally? Fasting as an essential regulator of immune responsesReviewFastingPaper
International Journal of Molecular Sciences·Mar 4Five Days Periodic Fasting Elevates Levels of Longevity Related Christensenella and Sirtuin Expression in HumansNon-randomized trial in 51 peopleInterventionsPaper
Obesity Research & Clinical Practice·Dec 25Ketogenesis and SIRT1 as a tool in managing obesityReviewObesityPaper
bioRxiv·Nov 26Ketogenesis restrains aging-induced exacerbation of COVID in a mouse modelPreprint: experiments in miceInterventionsPaper
Aging Cell·Oct 27CR reprograms acetyl-CoA metabolism and induces long-chain acyl-CoA dehydrogenase and CrAT expressionExperiments in animalsInterventionsPaper
Circulation Heart Failure·Sep 1Cardioprotective Effects of Sirtuin-1 and Its Downstream Effectors: Potential Role in Mediating the Heart Failure Benefits of SGLT2 (Sodium-Glucose Cotransporter 2) InhibitorsReviewSGLT2 inhibitorsPaper
Journal of Diabetes and Its Complications·Jun 5Role of ketogenic starvation sensors in mediating the renal protective effects of SGLT2 inhibitors in type 2 diabetesReviewSGLT2 inhibitorsPaper
Cell Reports·Apr 30Region-Specific Proteome Changes of the Intestinal Epithelium during Aging and Dietary RestrictionExperiments in miceDietary restrictionPaper
Circulation·Mar 18Role of Deranged Energy Deprivation Signaling in the Pathogenesis of Cardiac and Renal Disease in States of Perceived Nutrient OverabundanceReviewKidneyPaper
Nutrients·Oct 1Exogenous Ketones Lower Blood Glucose Level in Rested and Exercised Rodent ModelsExperiments in ratsExercisePaper
BMC Genomics·Jan 18RiboTag translatomic profiling of Drosophila oenocytes under aging and induced oxidative stressExperiments in fliesFatty acid β-oxidationPaper
JCI Insight·Aug 24Oral nitrite restores age-dependent phenotypes in eNOS-null miceExperiments in miceInterventionsPaper