International Journal of Food Sciences and Nutrition
Vitexin and isovitexin delayed ageing and enhanced stress-resistance through the activation of the SKN-1/Nrf2 signaling pathway
Experiments in wormsInterventions
Papers on Keap1
127 papers6 new in 30 days
Tuesday, August 22
Sunday, August 20
Wednesday, July 12
Tuesday, June 27
Thursday, June 8
Thursday, March 23
Journal of Ethnopharmacology
Mulberry leaves attenuate D-galactose-induced aging in vivo and in vitro
Experiments in wormsInterventions
Thursday, March 9
Frontiers in Pharmacology
Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway
Experiments in miceUrolithin A
Sunday, February 26
International Journal of Molecular Sciences
Melatonin Promotes the Development of Secondary Hair Follicles in Adult Cashmere Goats by Activating the Keap1-Nrf2 Signaling Pathway and Inhibiting the Inflammatory Transcription Factors NFκB and AP-1
Experiments in goatsMelatonin
Saturday, February 11
Sunday, November 20
Free Radical Biology & Medicine
Targeting NRF2-KEAP1 axis by Omega-3 fatty acids and their derivatives: Emerging opportunities against aging and diseases
ReviewOmega-3 fatty acids
Friday, November 18
Friday, October 28
International Journal of Molecular Sciences
Aberrant Transferrin and Ferritin Upregulation Elicits Iron Accumulation and Oxidative Inflammaging Causing Ferroptosis and Undermines Estradiol Biosynthesis in Aging Rat Ovaries by Upregulating NF-Κb-Activated Inducible Nitric Oxide Synthase: First Demonstration of an Intricate Mechanism
Experiments in ratsFerroptosis
Saturday, October 1
Cancer Drug Resistance
Base excision repair accessory factors in senescence avoidance and resistance to treatments
ReviewDNA repair
Saturday, September 24
Thursday, June 30
Wednesday, May 11
Journal of Biochemistry
NRF2 pathway activation attenuates ageing-related renal phenotypes due to α-klotho deficiency
Experiments in miceNRF2–KEAP1 antioxidant response
Monday, May 2
Sunday, March 13
The Journals of Gerontology, Series A
Chlorogenic Acid Activates Nrf2/SKN-1 and Prolongs the Lifespan of Caenorhabditis elegans via the Akt-FOXO3/DAF16a-DDB1 Pathway and Activation of DAF16f
Experiments in wormsInterventions
Monday, February 21
Sunday, February 20
Sunday, February 6
Monday, January 17
Phytotherapy Research
Urolithin A alleviates acute kidney injury induced by renal ischemia reperfusion through the p62-Keap1-Nrf2 signaling pathway
Experiments in miceUrolithin A
Friday, January 14
Journal of Advanced Research
Oxyphylla A ameliorates cognitive deficits and alleviates neuropathology via the Akt-GSK3β and Nrf2-Keap1-HO-1 pathways in vitro and in vivo murine models of Alzheimer's disease
Experiments in animalsInterventions
Monday, January 3
Research Square
Homocysteine-Potentiated Keap1 Promotes Neuronal Senescence via Inhibiting Ubiquitination of β-Catenin
Preprint: experiments in ratsCellular senescence
Saturday, December 25
Friday, October 29
Journal of Biotechnology
The down-regulation of melanogenesis via MITF and FOXO1 signaling pathways in SIRT1 knockout cells using CRISPR/Cas9 system
Experiments in cellsMechanisms
Saturday, July 17
The Journal of Nutritional Biochemistry
Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway
Experiments in miceSkin
Tuesday, June 15
Journal of Cellular Physiology
Oxidative stress in oocyte aging and female reproduction
ReviewMechanisms
Friday, May 21
Oxidative Medicine and Cellular Longevity
The Keap1-Nrf2 System: A Mediator between Oxidative Stress and Aging
ReviewMechanisms